Treatment (RX) of precocious puberty with the synthetic GnRH agonist buserelin (HOE 766)

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Leptin and adiponectin levels in girls with central precocious puberty before and during GnRH agonist treatment

PURPOSE The effects of gonadotropin-releasing hormone agonist (GnRHa) treatment on the energy metabolism in girls with central precocious puberty (CPP) are controversial. We focused the changes and related factors of serum levels of leptin and adiponectin in girls with CPP before and during GnRHa treatment. METHODS Thirty girls with idiopathic CPP were enrolled in the study. Their auxological...

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GnRH agonist treatment in girls with precocious puberty does not compromise post-pubertal uterine size.

BACKGROUND Prompted by findings of a hypoestrogenic state in girls during prolonged treatment with GnRH agonist and a close association of estradiol serum concentrations with uterine volume in puberty, this study sought to evaluate uterine and ovarian size in girls with precocious puberty (PP) during and after treatment and the effect of age or duration of treatment. METHODS Patients with idi...

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Serum Anti-Müllerian Hormone Levels in Precocious Puberty Girls according to Stage of GnRH Agonist Treatment

Few studies have investigated the long-term effects of gonadotropin-releasing hormone (GnRH) agonist treatment on the reproductive function of central precocious puberty (CPP) girls. In this cross-sectional study, we assessed the ovarian function by analyzing the serum anti-Müllerian hormone (AMH) levels of CPP girls. Our study included 505 CPP girls subdivided into 5 groups according to the Gn...

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GnRH agonist treatment for idiopathic central precocious puberty can improve final adult height in Chinese girls

Object To study the outcomes of GnRHa on final adult height in Chinese idiopathic central precocious puberty (ICPP) girls and the involved factor(s) that can predict height gain. Methods We conducted a retrospective analysis on 10 years of data obtained from three clinical hospitals from January 2005 to March 2015, and 101 girls with ICPP, who received GnRHa therapy for more than six months a...

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Evaluating the Efficacy of Treatment with a GnRH Analogue in Patients with Central Precocious Puberty

Objective. GnRH analogues (GnRHa) are used in the treatment of central precocious puberty (CPP). The purpose of this study was to evaluate the efficacy of treatment with a GnRHa (leuprolide acetate) in patients with CPP. Subjects and Methods. A total of 62 female child patients who had been diagnosed with CPP, rapidly progressive precocious puberty (RP-PP), or advanced puberty (AP) and started ...

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ژورنال

عنوان ژورنال: Journal of Steroid Biochemistry

سال: 1984

ISSN: 0022-4731

DOI: 10.1016/0022-4731(84)90489-8